HIV in Children
March 2014 NEWSLETTER
HIV IN CHILDREN
March 2014 Newsletter
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GRAND ROUNDS
A one and a half month old girl born to HIV infected parents presented with vomiting since 2 days and breathlessness since 1 day. Mother was diagnosed to be HIV infected during 5th month of gestation and received zidovudine (AZT) prophylaxis. She underwent elective caesarean section at 38 weeks of gestation. Baby was kept on formula feeds since birth and given AZT prophylaxis (2 mg/kg/dose qds). Birth weight of the child was 2.8 kg. On presentation, child had heart rate of 130/min, respiratory rate of 60/min. She was alert and active with present weight of 4 kg. She had a soft hepatomegaly and other examination findings were normal. Investigations showed:-
- Hemoglobin = 10 gm/dl
- WBC = 7,000/cumm [50% polymorphs, 48% lymphocytes]
- Platelets = Adequate
- Chest X-Ray = Normal
- CRP = Negative
- SGPT = 78 IU/L
- Venous blood gas = Metabolic acidosis with high anion gap.
- Serum lactate = elevated

How to treat the lactic acidosis in this child?

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