HIV in Children
November 2013 NEWSLETTER
HIV IN CHILDREN
November 2013 Newsletter
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GRAND ROUNDS
A 12 years old girl with vertically HIV-1 infection on antiretroviral therapy (ART) for past 8 years presented fever and diarrhea for one week. Initially, she was on Zidovudine (AZT) and Lamivudine (3TC) for 2 years and then was shifted to Stavudine (d4T), Didanosine (ddI) and Efavirenz (EFV) which has been continued till date. Her CD4 count has remained normal over this period and last HIV viral load done 2 months back was 400 copies/ml. On examination, she had tender hepatomegaly. Investigations showed:
• SGOT = 532 IU/L, SGPT = 484 IU/L.
• USG Abdomen = Fatty liver
• VBG = pH = 7.29, Bicarbonate = 15.9 mmol/L
• Serum cholesterol = 172 mg/dl, Triglyceride = 340 mg/dl.

What is the cause of the liver derangement?

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Question Of the Day
Q. If mother is HIV +ve what investigation of baby should be done? At what age? How long zidovir should be continued?
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Upcoming Conferences
4th Pediatric Infectious Diseases Conference on 17th November 2013,
Nehru Science Centre, Worli, Mumbai.
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HIV ARTICLE
>> Updated: Antiretroviral prophylaxis and breast feeding (includes WHO 2013 guidelines)
>> Updated: Antiretroviral Therapy (includes 2013 guidelines)
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NEW ARRIVAL
Infection in Children - Part 2

By Dr. Ira Shah
Case Rounds in Pediatric Liver Disorders
By Dr. Ira Shah
Tuberculosis
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Management of Pediatric HIV
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Infection in Children
By Dr. Ira Shah