HIV and Organ Dysfunctions - HIV in Children

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PREVENTION & TREATMENT

HIV Prevention and Treatment

	HIV & Immunization HIV-infected children should be protected from vaccine preventable diseases. Most vaccines recommended for
routine use can be administered safely to HIV-exposed or HIV-infected children.

Transmission of HIV In children, the mode of transmission is predomi-nantly mother to child (vertical transmission) with
transmission rate varying from 25% to 40%. The transmission can occur intrauterine,intrapartum.

Antiretroviral therapy (ART) For HIV infected Children
ART helps in improving and restoring the immune system functioning and decreasing the mortality and morbidity associated with HIV infection.ART does not cure HIV infection and requires very close adherence in order to be effective and prevent emergence of resistance.

DIAGNOSIS

HIV Diagnosis

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Journal Watch

	HIV Monitoring Immunological changes in HIV-1 infection include a decrease in CD4+ cells, a transient increase in CD8+ cells,
total lymphocytes and inversion of the CD4/CD8 ratio.

HIV Diagnosis
Serological diagnosis of HIV infection is only reliable after 15-18 months of age. Infants infected with HIV must be diagnosed as rapidly as possible.

HIV and Clinical Manifestations
Systemic and pulmonary findings were common in the first HIV infected children.In India, common clinical presentations are hepatosplenomegaly, lymphadenopathy, tuberculosis, failure to thrive and chronic diarrhea.

INTERACTIVES

HIV in Children : Interactives

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