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UNIVERSAL PRECAUTIONS
Dr. Ira Shah
M.D, DNB, DCH(Gold Medalist), FCPS

When treating HIV infected individuals, it is essential to take care of basic precautions to prevent transmission of HIV to the health care worker. There have been few cases of health care workers becoming HIV infected due to needle stick injuries and contact with infected secretions. Hence certain guidelines need to be followed when handling these children.
    - While doing any procedure in the child, such as lumbar puncture, blood collection, the    attendant should use gloves, gowns and protective eye wear.

    - A surgeon should wear double gloves during surgery in an HIV infected child along with    above measures.

    - In case of spilling of blood, urine, vomit, stools or other body fluids, the spills should be    cleaned wearing disposable gloves and wiped with disposable rags or paper towels. The    surface should be cleaned with a bleach solution (1/4 cup bleach to 2.5 litres of water). The    surface should be washed and air-dried. The disposable gloves, rags should be discarded in    a leak-proof plastic bag.

    - Instruments such as laryngoscopes if used in HIV infected child should be sterilized with    hypochloride solution.

    - In case of needle stick injury, the exposure site should be washed with soap and water and    a disinfectant can be used. If the wound is deep or large volume of infected material has    been splashed over the exposure site then an expanded regimen of post-exposure    prophylaxis for 28 days is recommended consisting of either:
Zidovudine 300 mg bid               Stavudine 30/40 mg bid
          +                           OR                     +
Lamivudine 150 mg bid               Lamivudine 150 mg bid

Expanded regime


Zidovudine 300 mg bid               Stavudine 30/40 mg bid
          +                           OR                     +
Lamivudine 150 mg bid               Lamivudine 150 mg bid
                                       &
                               Indinavir 800 mg 8 hourly
                                       OR
                               Nelfinavir 750 mg tid
                                       OR
                               Efavirenz 600 mg HS.

    - Incase of contact with small volume of blood or contact on open wound or mucus membrane    then a basic regimen of post exposure prophylaxis or 28 days is recommended consisting    of:

    - Post exposure prophylaxis should be initiated within 1-2 hours of exposure ideally and    preferably within 24 hours of exposure.

    - Health workers with possible exposure to HIV infection should undergo HIV antibody testing    regularly for at least 6 months following exposure.

Reference:


Shah Ira. Management of Pediatric HIV. Publisher: www.pediatriconcall.com Mumbai, 2005:55-56.

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