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Zidovudine toxicity in a 15 day old
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Dr Ira Shah
A Day 15 old girl born to HIV infected parents came for first follow up visit. Mother was diagnosed to be HIV infected at 6 moths of gestation and had received Zidovudine for 3 months. Baby was born vaginally and not on breast feeds. Birth weight of the child was 3 kg. Baby was started on Zidovudine 2 mg/kg /dose 6 hourly and was advised to give 0.6 ml qds of Zidovudine syrup (5 ml = 50 mg) every 6 hourly. However, on interviewing the mother, it was found that she was giving the baby 6 ml 6 hourly instead of 0.6 ml 6 hourly. However, the baby had no other symptoms. On examination, her weight was 3.5 kg and examination findings were normal.
 
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